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BIO Magazine - Enaminocarbonyl compounds and their use Δεκέμβριος 2015
Δεκέμβριος 2015 No38

BIO Patent

Enaminocarbonyl compounds and their use
Enaminocarbonyl compounds and their use

The subject of the present invention are enaminocarbonyl compounds, containing a 5-member ring containing a carbonyl group and an enamine group in a side chain attached to a carbon atom adjacent to the carbon atom of the carbonyl group, as well as the use of these compounds as taste modifiers.

In recent times, the number of persons suffering from obesity, hypertension, cardiac and renal disease as well as tooth cavities has increased significantly. These diseases can be caused by the excessive ingestion of saccharose or other caloric sweeteners. Persons afflicted with the abovementioned diseases, diabetics, as well as persons wishing to maintain or decrease their body mass can use artificial sweeteners. The sweeteners impart a sweet taste to the consumed foodstuffs, and at the same time help reduce their calorie content in comparison to products sweetened with ordinary sugar (saccharose) and other caloric sweet substances. Sweeteners are not only used in foodstuffs, but in many other products as well, such as toothpaste, chewing gum, and mouthwash in order to improve their taste (Alternative Sweeteners, 3rd Edition, Revised and Expanded, Lyn O’Brien Nabors Ed., Marcell Dekker, Inc, 2001).

Many low-calorie synthetic sweeteners are known such as acesulfam-K, aspartame, sodium cyclamate, saccharine, or recently sucralose. Despite the fact that a number of them are currently admitted for general marketing in Poland and other nations, a real need still exists to seek out new classes of synthetic compounds which could be used as sweeteners.

 

Read full patent specification

Proprietor:
Instytut Chemii Organicznej, Polska
Akademia Nauk
01-224 Warszawa (PL)

Inventors: 
KRAJEWSKI, Piotr
03-982 Warszawa (PL)

WOZNIAK, Agnieszka
00-478 Warszawa (PL)

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